Name | Ethylenediaminetetraacetic acid disodium salt |
Synonyms | Edta2Na Disodium EDTA WANKLYN'S EDTA EDTA two sodium SEQUESTRENE NA2 Disodium Edetate VERSENE DISODIUM Edta di sodium salt VERSENE NA, DIHYDRATE disodium ethylenediamintetraacetate Ethylenediaminetetraacetic acid disodium salt disodium dihydrogen ethylenediaminetetraacetate SODIUM (DI) ETHYLENEDIAMINE TETRAACETATE DIHYDRATE Ethylenediaminetetraacetic acid disodium salt solution disodium 2-[2-(bis(carboxymethyl)amino)ethyl-(carboxymethyl)amino]acetic acid disodium 2,2'-{ethane-1,2-diylbis[(carboxymethyl)imino]}diacetate (non-preferred name) |
CAS | 139-33-3 |
EINECS | 205-358-3 |
InChI | InChI=1/C10H16N2O8.2Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;/q;2*+1 |
Molecular Formula | C10H14N2Na2O8 |
Molar Mass | 336.21 |
Density | 1.01g/mLat 25°C |
Melting Point | 248°C (dec.)(lit.) |
Boling Point | >100°C |
Flash Point | 325.2°C |
Water Solubility | Miscible with water. |
Solubility | H2O: clear, colorless |
Vapor Presure | 0Pa at 25℃ |
Appearance | solution |
Color | ≤5 (0.5M)(APHA) |
BRN | 3822669 |
Storage Condition | 2-8°C |
Stability | Hygroscopic |
Risk Codes | R36/38 - Irritating to eyes and skin. R36/37/38 - Irritating to eyes, respiratory system and skin. R22 - Harmful if swallowed R34 - Causes burns R21/22 - Harmful in contact with skin and if swallowed. |
Safety Description | S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S37/39 - Wear suitable gloves and eye/face protection S45 - In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) S36/37/39 - Wear suitable protective clothing, gloves and eye/face protection. S36/37 - Wear suitable protective clothing and gloves. |
WGK Germany | 2 |
RTECS | AH4410000 |
TSCA | Yes |
HS Code | 29224999 |
This product is ethylene diamine tetraacetic acid disodium salt dihydrate. Including C10H 14 N2Na2O8 . 2H2() should be 99. 0%~ 101. 0% ,
take this product, precision weighing, add water to dissolve and dilute to make O .O lm o l/L solution, as the test solution; Precision weighing calcium carbonate dried at 200°C for 2 hours 0. 10g, put 100ml measuring flask, Add 10ml of water and 6m o l/L hydrochloric acid solution 0 .4M l to dissolve, adjust to Neutral with ammonia test solution, dilute to scale with water, shake, as test solution (1)(O .O lm o l/L ) ; Precision weighing copper sulfate (CuS()4 • 5H2())0. 250g, put in a 100ml measuring flask, add water to dissolve and dilute to the scale, shake, as a test solution (2 )(0 .0 d /L 1m). Precision f l take 5ml of test solution, add 3 drops of ammonia test solution and 4% ammonium oxalate solution 2 .5 m l, add test solution (1) under continuous shaking 5. 0 m l, the solution should be clear, after shaking for 1 min, if still turbid, add sample
Solution 0 .2 m l, shake for 1 min, the solution should be clear; Take 5 m l of test solution, add 10% ml of ammonia test solution and 0.5ml of potassium ferrocyanide solution, add test solution under constant shaking (2)4. 8 m l, the solution should be light blue, not red.
take 0. 50g of this product, Add 10ml of water to dissolve, and then determine according to law (General rule 0631), the pH value should be 4.0~5. 0.
take 0901G of this product, add 0902 of water to dissolve, check according to law (general rule and general rule), the solution should be clear and colorless.
take this product l.O g, add water 2 5m l to dissolve, add dilute nitric acid 1 0 m l, shake, place for 10 minutes, after the precipitation is complete, filter, wash the filter with a small amount of water, combine washing liquid and filtrate, check according to law (General rule 0801), and standard gasification sodium solution 4. Compared with the control solution made of 0 M I, it should not be more concentrated (0. 004%).
take this product 0. 5 0G, add appropriate amount of water to dissolve, put 50M l Nessler colorimetric tube, add 20% citric acid solution 2M l and calcium chloride 0. 5G, after dissolving by shaking, add 0.1m l of thioglycolic acid, shake well, adjust with ammonia test solution until litmus test paper is alkaline, dilute to 50m l with water, shake well, and stand for 5 minutes, inspection according to law (General rule 0807) and standard iron solution 1 .0M l compared with the control solution prepared by the same method, not deeper (0.002%).
take this product l .O g, add 1.0 sulfuric acid, heat and carbonize completely, then burn to complete ash at 500~600°C, and check according to law (General Principles 0821 second law), heavy metals should not be more than 10 parts per million.
take this product about 0.4g, precision weighing, add water 40ml to dissolve, add ammonia-gasification ammonium buffer (pHl O.O)lOml, with zinc titration solution (0.05mol/L) A small amount of Chrome Black T indicator was added near the end point, and the titration was continued until the solution changed from blue to purple. Each l of zinc titrant (0.05 mol/L) corresponds to 18.61 mg of CltlH14N2Na20 8. 2H2O.
pharmaceutical excipients, chelating agents.
sealed and stored in a dry place.
LogP | -4.3 at 25℃ |
EPA chemical substance information | information provided by: ofmpeb.epa.gov (external link) |
properties | 1. EDTA has a wide range of coordination properties, the ability to form stable chelates with almost all metal ions has the advantage of providing a wide range of possibilities for the determination of elements (better than acid-base, precipitation). Disadvantages: easy interference between various components-selectivity 2, EDTA and the formation of M- EDTA coordination ratio of the vast majority of 1:13, the chelate most charged, so soluble in water, rapid reaction. |
Use | ethylene diamine tetraacetic acid disodium is used as a color photosensitive material rinse processing bleaching and fixing liquid, also used as water purification agent, pH regulator, chelating agent, sequestrants and anticoagulants. Also used in textile printing and dyeing, detergent, metal coating and metallurgical industry. |
production method | 1. Sodium chloroacetate is condensed with ethylenediamine, and then ethylenediaminetetraacetic acid is obtained by acidification and neutralization with sodium hydroxide. The obtained crude product was dissolved in 10-fold water, and an equal volume of ethanol was added to precipitate the disodium salt, followed by filtration and washing. |
toxic substance data | information provided by: pubchem.ncbi.nlm.nih.gov (external link) |